A drug allergy is a reaction by your immune system. If you
are allergic to a drug, even a small amount of the drug can
trigger a reaction. These reactions range from
mild to life-threatening.
How does it occur?
Your immune system treats a drug as a foreign substance and
tries to protect you from it. The drugs most likely to
cause these problems are:
- antibiotics
- certain vaccines
- anti-seizure medicines
- contrast dyes used for some x-rays
- some heart and cancer drugs
- certain kinds of insulin
- local anesthetics like novocaine.
Some people are allergic to penicillin. Anyone can develop
an allergy to penicillin after exposure to it. Having an
allergy to penicillin does not mean you are allergic to all
antibiotics.
What are the symptoms?
The most common symptoms are itching, redness, swelling of
the skin, welts, and a runny nose. Symptoms of a drug
allergy can occur within minutes of taking the first dose,
or they can begin several days after taking the drug. About
half of all allergic reactions occur 1 week after starting
the drug. Most symptoms go away 3 to 5 days after you stop
taking the drug.
Anaphylaxis is a life-threatening allergic reaction. This
reaction is sudden, severe, and involves the whole body.
Symptoms of anaphylaxis include:
- abdominal pain or cramping
- confusion
- diarrhea
- dizziness
- fainting
- fast or pounding heartbeat
- nausea and vomiting
- skin rash or hives
- swelling in the lips, face, or throat
- trouble breathing with wheezing or a hoarse voice.
How is it diagnosed?
Your health care provider will ask about your symptoms and
the drugs you have taken. Tell your provider about all
your medicines (prescription, nonprescription, supplements,
natural remedies, and vitamins).
If you have an allergic reaction, your provider may
recommend that you see an allergy specialist for testing.
For example, if a penicillin allergy is suspected, the best
way to confirm it is with a skin test.
How is it treated?
Anaphylaxis is life-threatening. If you think you are
having severe allergic reaction, get emergency medical care
or call 911 for help. A severe or life-threatening reaction
may require an injection of epinephrine (also called
adrenaline) or a corticosteroid, such as hydrocortisone. A
mild reaction may be treated with an antihistamine.
How long will the effects last?
The effects of the allergic reaction last from several
minutes to hours, depending on how much of the drug you took
and the severity of your allergy.
To prevent allergic reactions in the future, you must avoid
taking the drug that caused the reaction. If you have had
a severe allergic reaction, wear a medical alert bracelet
at all times. Tell all health care providers who treat you
if you have ever had an allergic reaction to any medicine.
Be sure to check all labels for the names of these drugs
before taking any medicines or natural remedies.


Disclaimer: This content is reviewed periodically and is subject to
change as new health information becomes available. The
information provided is intended to be informative and educational and is not a
replacement for professional medical evaluation, advice, diagnosis or
treatment by a healthcare professional.
HIA File ALL3107F.HTM Release 9.0/2006. Copyright © 2006 McKesson Corporation and/or one of its subdiaries. All Rights Reserved.
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