What is fifth disease?
Fifth disease is an infection caused by human parvovirus
B19. The name fifth disease comes from being the fifth
childhood disease with a pink-red rash to be described.
What is the cause?
Almost all children get fifth disease. Most children get
the disease when they are school age. It occurs most often
in the winter and spring months.
Adults can get fifth disease if they are not immune from
childhood. They may have no symptoms or may develop the
typical rash of fifth disease, as well as joint pain, and
swelling. Joint pain, especially in the knees, may last for
1 to 3 months or longer. These adults should seek the
advice of their health care provider. Although many people
have no symptoms other than the rash, the disease can last
from a few days to several weeks.
What are the symptoms?
Most children with the infection feel well. The person
exposed to fifth disease usually does not get ill for 4 to
14 days after being exposed. It can take as long as 20
days. Some children develop symptoms such as a sore throat,
slight fever, headache, and tiredness.
Several days later, for both adults and children, a rash
appears on the cheeks. The rash looks as though the cheeks
have been slapped. This facial rash feels hot and sometimes
itches. After a few days, the rash may spread to the upper
body and arms in a lacy pattern. The rash may come and go
for 3 weeks, especially after warm baths, exercise, and sun
exposure.
How is it spread?
Fifth disease is spread when an infected person sneezes or
coughs or touches their face and then touches another
person. People can infect others for a week before the rash
appears. Frequent hand washing helps decrease the chance of
becoming infected.
The human parvovirus B19 that causes fifth disease only
infects humans. Dogs and cats may be immunized against
parvovirus, but it is a different parvovirus that does not
infect humans. A person cannot catch human parvovirus from
a dog or cat and an animal cannot catch the disease from a
human. Once you have had fifth disease, you cannot get it
again.
Fifth disease poses a risk during the first half of
pregnancy. Babies infected with fifth disease before birth
may develop severe anemia. People who have a weakened
immune system or those with sickle cell disease are also at
risk. If you have been exposed to fifth disease, avoid
contact with pregnant women, people who are
immunocompromised, and those who have sickle cell disease.
Fifth disease does not require treatment.


Disclaimer: This content is reviewed periodically and is subject to
change as new health information becomes available. The
information provided is intended to be informative and educational and is not a
replacement for professional medical evaluation, advice, diagnosis or
treatment by a healthcare professional.
HIA File INF4508F.HTM Release 9.0/2006. Copyright © 2006 McKesson Corporation and/or one of its subdiaries. All Rights Reserved.
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