What is cortisone?
Cortisone is in a family of medicines called
corticosteroids, which are strong anti-inflammatory drugs.
Corticosteroids are used for many conditions. They can be
taken by mouth or in a variety of other ways including
creams, inhalers, or injections (shots).
Because they have a similar name, corticosteroids are sometimes
confused with anabolic steroids. They are not the same.
Anabolic steroids are a group of drugs that increase muscle
mass and strength. These are often used illegally by
athletes and can have many harmful side effects.
What is a cortisone injection used for?
A cortisone shot is often used to give short-term pain
relief and reduce the swelling from inflammation of a joint,
tendon, or bursa (sac that provides cushion in a joint).
These problems are common in knee, elbow, and shoulder
joints. Reducing the swelling helps relieve pain and
discomfort and can speed up recovery from an injury.
A shot of cortisone may also be given to reduce inflammation
over the whole body (for example, if you have an allergic
reaction or a flare-up of rheumatoid arthritis).
How is the shot given?
The corticosteroid medicine is usually mixed with a local
anesthetic and then injected into the painful area. At
first, the shot may feel uncomfortable, but the local
anesthetic will help with the discomfort.
What happens after I get the shot?
When the anesthetic wears off, the area where the shot was
given may be quite sore. Your health care provider may
recommend putting an ice bag on the area for 20 to 30
minutes every 3 to 4 hours after the shot and taking an
anti-inflammatory medicine (such as ibuprofen). The
cortisone will start to reduce the inflammation and give you
pain relief within 2 to 3 days. In some cases, the
cortisone will permanently relieve your symptoms. In other
cases, the pain relief is temporary and can last anywhere
from a couple of weeks to years.
How well the shot works depends on many things, including
the amount of drug given, the cause of the problem, if the
shot is given in the right area, and other factors.
Many chronic (ongoing) inflammatory conditions are caused by
overuse. If you continue activities that overuse the
injured area, the inflammation may return and the cortisone
shot will probably not help that much.
What are the risks?
Side effects from cortisone shots are rare. Possible side
effects at the site where the shot was given include:
- slight bruising of the skin
- shrinkage of the fatty tissue under the skin where the
shot was given
- increase in pain after the shot
- infection
- weakening of the tendons or tendon rupture
- allergic reaction to the medicine.
Diabetics may have a temporary increase in their blood sugar
after a shot.
Cortisone can temporarily weaken the immune system. While
receiving these shots, you should not get certain vaccines.
Also, avoid contact with anyone who has chickenpox or
measles, especially if you have never had these diseases.
Your immune system may not be strong enough to fight off the
infection while you are taking cortisone.


Disclaimer: This content is reviewed periodically and is subject to
change as new health information becomes available. The
information provided is intended to be informative and educational and is not a
replacement for professional medical evaluation, advice, diagnosis or
treatment by a healthcare professional.
HIA File MED4278F.HTM Release 9.0/2006. Copyright © 2006 McKesson Corporation and/or one of its subdiaries. All Rights Reserved.
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