What are moles?
Moles are small bumps or areas of skin color change that can
occur on any part of the skin. Most moles are brownish but
they can be flesh colored, blue, or black. The color is due
to a pigment called melanin in your body's cells. Most
people have at least a few moles.
How do they occur?
Some moles are present at birth. Most appear on the skin
during the first 20 years of life, especially during
puberty. They are caused by an overproduction of melanin in
clumps of skin cells. The cause of this melanin
overproduction is not known.
Moles start out as a flat brown or black spot much like a
freckle, but they may become raised. Many grow larger and
some develop hairs.
Are moles unhealthy?
Most moles are harmless. Some moles, however, may be
considered unsightly because of their appearance or
location.
Rarely (about one in a million), a mole undergoes cancerous
change to become a malignant melanoma. Malignant melanoma
is the least common but most dangerous form of skin cancer.
Research suggests that malignant melanoma in adults may be
related to sunburn in childhood.
How are they treated?
Because most moles are harmless, they usually need no
treatment. Some may be removed for cosmetic reasons. Hairs
on moles that are unsightly can be kept trimmed or the
hairs can be removed permanently by a dermatologist.
Malignant melanomas are removed surgically. The surgery may
be followed with radiation therapy or anticancer drugs.
What changes in moles should I watch for?
You should have your health care provider check any change
you notice in a mole. In particular, watch for:
- Moles that appear in large numbers (greater than 100).
- A change in size (especially if the mole spreads and
becomes broader).
- A change in border (the outline of the mole becomes
irregular).
- A change in shape in which one half of the mole does not match the other.
- A change in color or different shades of color appearing in the same mole.
- A change in surface appearance (for example, the mole begins to scale, crust, ooze, or bleed).
Additionally, if moles itch, hurt, bleed, swell, or come
back, they need medical evaluation.


Disclaimer: This content is reviewed periodically and is subject to
change as new health information becomes available. The
information provided is intended to be informative and educational and is not a
replacement for professional medical evaluation, advice, diagnosis or
treatment by a healthcare professional.
HIA File SKN4862F.HTM Release 9.0/2006. Copyright © 2006 McKesson Corporation and/or one of its subdiaries. All Rights Reserved.
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