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The lining of the womb reacts to female hormones throughout life. A balanced cycle of the female hormones, progesterone and estrogen, is needed to get a normal period. If the estrogen part of the cycle becomes too strong, the lining of the uterus will overgrow. This thickened lining causes heavy and irregular bleeding. Sometimes this leads to a lower blood count. The cycle can be shorter or longer than usual, even to the point of having no periods for many months.
Women at risk for this overgrowth, in addition, will usually have one of the following:
* a severe weight problem,
* the inability to get pregnant due to ovarian problem, called polycystic ovarian syndrome, or
* medical problems, such as diabetes or high blood pressure.
Testing and treatment depend on how long and severe the problem has been going on. The desire for children is considered as well. Because women often get used to heavier periods without complaining, a blood count can tell how bad the problem has become. A sample of the lining may be taken with a tiny straw-like instrument before treatment is started. This will test for any other causes of bleeding, like cancer. At this point, treatment can begin, usually with hormones to correct the problem. Birth control pills, progesterone tablets or shots, and fertility drugs are used with young women. Surgery is rarely needed.
Women over 40 who develop endometrial overgrowth are at higher risk for a cancer of the uterine lining. When not treated for more than 1 year, twenty-five percent of these women will get cancer. A sampling of the lining shows signs of these changes. If no cancer is found, treatment will usually begin with progesterone therapy and close follow up is needed by a health care provider. Most women find their bleeding will become less severe and more regular with treatment. Advanced cases may require surgery to remove both the uterus and the out of balance ovaries. Doing this will prevent cancer from developing.
Women of all ages can have endometrial overgrowth. Women in menopause who take hormones need to take both estrogen and progesterone to prevent any overgrowth.
Copyright © 1997 National Health Enhancement Systems, Inc.
(602) 230-7575. All rights reserved. Information in this document is subject to change
without notice.
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